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Category «Proteomics»

New Publication – Proteomics of Advanced and Metastatic Melanoma

We are excited to announce the publication of our latest research paper, “Proteomic profiling of cutaneous melanoma explains the aggressiveness of distant organ metastasis,” in the Journal of Experimental Dermatology. Despite advancements in managing metastatic melanomas, patient survival rates remain low. Therefore, our team set out to better understand the proteome-wide changes associated with melanoma …

Non-invasive proteomic analysis of Mycosis Fungoides

We are pleased to share the news that our recent article entitled “Tape Stripped Stratum Corneum Samples are Suitable for Diagnosis and Comprehensive Proteomic Investigation in Mycosis Fungoides” has been accepted for publication at the journal of Proteomics Clinical Application – DOI:10.1002/prca.202200039. This study, for the first time, evaluates the use of tape-stripping and proteomic …

Australian Society for Dermatology Research (ASDR) Conference 2022

By Rachel Teh, PhD Candidate: Finally, an opportunity to attend a conference in person! The annual Australian Society for Dermatology Research (ASDR) conference was held at the beautiful Translational Research Institute (TRI) in Brisbane from the 4th to the 6th of August 2022. After enduring the COVID-19 pandemic and subsequent lockdowns, this was a welcome …

PhD in Atopic Dermatitis with Research Scholarship open to applicants

We are pleased to announce that a Ph.D. scholarship valued at up to $35,000/year for up to 3.5 years, to work on an exciting research project with our team is open for application. The project involves proteomic studies of clinical samples of atopic dermatitis or eczema for the identification of protein biomarkers and molecular alterations …

Pfizer awarded funding to members of the CTSR to study atopic dermatitis

We are pleased to announce that Professor Fernandez-Penas (principal investigator) and Dr Ali Azimi were successful in securing AUD $229000.00 from Pfizer Pharmaceuticals to study clinical samples of patients with atopic dermatitis (AD) for the identification of protein biomarkers and molecular pathways that correlate with different ethnicities. The findings of this novel approach will aid …

Our recent publication – Skin-specialised proteomics library

Our dataset brief has been accepted for publication by the Journal of Proteomics. It features our very own in house skin cancer specialised protein library suitable for data-independent applications. We used proteins collected from various sample types such as formalin-fixed paraffin-embedded samples of skin biopsies, human skin cancer cell lines, and tape stripping of the …

Will storage temperature affect the proteome profile of skin samples collected by tape-stripping?

For molecular profiling analysis including proteomics (large-scale analysis of proteins), the human samples are stored at temperatures lower than −20°C immediately after collection. However, the storage and transport of human samples at −20°C or lower temperatures remain a challenge due to the lack of required personnel and infrastructure for frozen biospecimen storage and transport, especially …

The SW-TCRC ECR Accelerator Grant Awarded to Dr Ali Azimi

We are pleased to announce that Dr Ali Azimi, a member of the CTSR, was this week awarded the Sydney West Translational Cancer Research Centre (SW-TCRC) Early Career Accelerator Grant. The grant which includes salary support and direct research costs will allow Dr Azimi to continue his research works involving the proteomic investigation of early melanoma …

NEW PUBLICATION: Proteome changes between primary and metastatic cutaneous SCC

We are delighted to have our research paper entitled “Investigating proteome changes between primary and metastatic cutaneous squamous cell carcinoma using SWATH mass spectrometry” accepted for publication in the Journal of Dermatologic Science. The pre-print is published online and accessible here. In this study, we used our SWATH mass spectrometry platform to investigate the proteome …