Westmead Dermatology
Striving towards disease-free skin
We are excited to announce the publication of our latest research paper, “Proteomic profiling of cutaneous melanoma explains the aggressiveness of distant organ metastasis,” in the Journal of Experimental Dermatology. Despite advancements in managing metastatic melanomas, patient survival rates remain low. Therefore, our team set out to better understand the proteome-wide changes associated with melanoma …
We are pleased to share the news that our recent article entitled “Tape Stripped Stratum Corneum Samples are Suitable for Diagnosis and Comprehensive Proteomic Investigation in Mycosis Fungoides” has been accepted for publication at the journal of Proteomics Clinical Application – DOI:10.1002/prca.202200039. This study, for the first time, evaluates the use of tape-stripping and proteomic …
Dermatology consultation is a valuable inpatient service in hospitals. Adherence rates to consultative advice in international literature range between 67.4% and 93%. In the second part of our study about inpatient consultations, that has been recently published in the Australasian Journal of Dermatology, we have identified that adherence rates to suggested investigations (61.3%) and management …
Our dataset brief has been accepted for publication by the Journal of Proteomics. It features our very own in house skin cancer specialised protein library suitable for data-independent applications. We used proteins collected from various sample types such as formalin-fixed paraffin-embedded samples of skin biopsies, human skin cancer cell lines, and tape stripping of the …
Dermatology consultation has been shown to have a significant beneficial impact on admitted hospital patients with concurrent or newly diagnosed skin conditions. In this study, we aimed to determine the change in diagnosis and management after dermatology consultation at Westmead Hospital. We analysed 306 consecutive consultations. In 44% of cases, the requesting team did not …
For molecular profiling analysis including proteomics (large-scale analysis of proteins), the human samples are stored at temperatures lower than −20°C immediately after collection. However, the storage and transport of human samples at −20°C or lower temperatures remain a challenge due to the lack of required personnel and infrastructure for frozen biospecimen storage and transport, especially …
We are delighted to have our research paper entitled “Investigating proteome changes between primary and metastatic cutaneous squamous cell carcinoma using SWATH mass spectrometry” accepted for publication in the Journal of Dermatologic Science. The pre-print is published online and accessible here. In this study, we used our SWATH mass spectrometry platform to investigate the proteome …
We are pleased to announce that our paper investigating the suitability of non-invasively collected (tape-stripped) stratum corneum samples from the patients with actinic keratosis for downstream proteomic investigation has been published in the Journal of Proteomics Clinical Application. Our paper is one more step in the development of new diagnosis techniques for actinic keratosis using …
Instagram and Snapchat users have positive attitudes about tanning and more frequently tanned intentionally within the last year. Lisa Abbot and our team at Skin & Cancer Foundation Australia has studied the relationship between Social Media, Selfies and Tanning. Younger Australians and females feel more attractive when tanned and tanned intentionally in the last year. …
