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Category «Oncodermatology»

Our first New England Journal of Medicine: Nicotinamide for Skin Cancer Chemoprevention

Prof Diona Damian and Prof Gary Halliday have been working for many years on the effects of nicotinamide in skin cancer, from basic research to clinical studies. This publication is one of the latest outcomes of their work, and Westmead Dermatology is honoured to have been part of this study. Bonita, Pablo, Gaya and Nira …

Cutaneous Side Effects of Novel Anti-Melanoma Drugs

A/Prof Pablo Fernandez-Peñas was invited to attend the 7th Annual Meeting of the Asian Society for Pigment Cell Researchin Shanghai (China). He reviewed our papers on the Cutaneous Side Effects of BRAF inhibitors, MEK inhibitors, anti-CTLA4 and anti-PD1 therapies (Publications) and new results not yet published. Although melanoma is not as a big issue in most …

Sun protection is not just for summer

A/Prof Pablo Fernandez-Peñas was interviewed regarding sun protection and winter months. This interview appeared in the Manly Daily newspaper. The message is clear: “We can’t feel UV light, and the heat sensation is not related to the amount of UV light”. If you want to read the rest of the interview, you should be able …

Cutaneous Toxic Effects of BRAF Inhibitors Alone and in Combination With MEK Inhibitors

We have reviewed, in our population of patients with metastatic melanoma on targeted therapies, the cutaneous side effects of BRAF single agent (Dabrafenib or Vemurafenib) and the combination therapy (Dabrafenib + Trametinib). There are minimal differences between Dabrafenib and Vemurafenib (being photosensitivity the most important), but there are very significant differences between Dabrafenib and the …

Proteomic Data Analyses Using IPA

Often, it is very challenging to analyze and interpret the large data generated by techniques such as microarray and mass spectrometry. To overcome this issue, there have been few bioinformatics tools such as Ingenuity Pathway Analysis (IPA) developed that use the information already available in the literature to map the set of experimental data to …

What’s new in Melanoma – GP Information Session

Department of Dermatology in conjunction with the Westmead Melanoma Unit and Sydney West Translational Cancer Research Centre is hosting a free information evening for GPs on Thursday 30th of July 2015 (6.30 to 8.30pm) held at Westmead Hospital, Lecture Theatre 3, Education Block. This information session covers the latest developments in diagnosis and treatment available …

What is Mass Spectrometry?

Mass Spectrometry or MS is one of the advanced techniques that is used to systematically study and examine a large number of proteins in a cell, tissue or an organism. Recently, with advancement in the area of cutting edge proteomic technology, MS has become the primary tool for differential proteomic analyses, identification of protein biomarkers …